Itopride (INN) (brand name Ganaton) is a prokinetic benzamide derivative unlike In general: ℞ (Prescription only). Pharmacokinetic . the elderly. Little information is available at this time regarding the safe use of itopride during pregnancy. LEVITRA safely and effectively. See full prescribing information for. LEVITRA. LEVITRA (vardenafil hydrochloride) tablets, for oral use. Initial U.S. Approval: Itopride Hydrochloride. NAME OF THE MEDICINAL PRODUCTS. Ganaton 50 mg tablets. COMPOSITION OF THE MEDICINAL PRODUCT. 1 tablet contains

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When analyzed by symptom, the improvement rate scored as “moderate” or better was However, this does not necessarily indicate that itopride is not effective or safe. Itopride Latest prescription information about Itopride.

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In clinical trials Phase I to Phase IIIitopride hydrochloride was well tolerated and no serious adverse reactions were reported. Peak plasma levels C max 0. The conclusion of this study revealed that itopride is devoid of any abnormal effect on QT interval. Gepride 50mg Intra Labs India Pvt. Itopride may not be indicated for those suffering from Parkinson’s disease or other conditions involving dopamine regulation issues.

Itopride and Pregnancy Caution when used during pregnancy.

Itopride (Rabibit-ISR) Drug Information – Indications, Dosage, Side Effects and Precautions

Itopride is primarily eliminated via the kidneys having an elimination half-life of approximately 6 hours. The action of itopride hydrochloride is highly specific for the upper gastrointestinal tract. There are no adequate and well-controlled studies in pregnant women. It is very soluble in water, freely soluble in methanol or in glacial acetic acid, sparingly soluble in ethanol itoprode practically insoluble in acetic anhydride or in ether.


Itopride is typically taken three times a day. Itopride hydrochloride is a substituted benzamide. Why is Itopride Prescribed?

Itopride information from DrugsUpdate

Atropine Hyoscyamine Quaternary ammonium compounds: The primary metabolite in humans is the N-oxide generated by oxidation of the tertiary amine N-dimethyl group. The information should not be used for either diagnosis or treatment or both for any health related problem or disease.

The activity of itopride hydrochloride has been evaluated in 2 pivotal studies: The Final Global Prescriibing Ratings showed that the degree of improvement was “moderate improvement” or better in Itopride was shown to significantly improve symptoms in patients with functional dyspepsia and motility disorders in placebo-controlled trials.

Pharmacokinetics Itopride increases acetylcholine concentrations by inhibiting dopamine D2 receptors and acetylcholinesterase. Antiulcer drugs eg, cimetidine, ranitidine, teprenone and cetraxate do not affect the prokinetic action itoprjde itopride. Your comments are automatically posted once they are submitted.

In conscious dogs, itopride hydrochloride activates propulsive rpescribing motility through dopamine D2 receptor antagonistic actions and dose-dependent inhibition of acetylcholinesterase.

This means it is still under development and may contain inaccuracies. A double-blind comparative study evaluated patients diagnosed with functional, non-ulcer dyspepsia chronic gastritisacute gastric mucosal lesions AGMLgastric polyps with complaints of upper abdominal fullness, heaviness of the stomach, epigastric pain, nausea, vomiting, heartburn, loss of appetite, discomfort, etc.

There are no known effects of itopride hydrochloride on labor or delivery. In single-dose studies in dogs, itopride hydrochloride was shown to promote gastric emptying.


There were no significant differences observed between the 2 groups. Drugs A – Z.

Itopride (Rabibit-ISR) – Indications, Dosage, Side Effects and Precautions

precribing No teratogenic effect was observed in preclinical studies. Consult with your healthcare professional before taking any medication. Moreover, itopride has no affinity for the 5-HT 4 receptors, unlike other benzamides such as cisapride and mosapride, which are 5-HT 4 agonists. It does not affect serum gastrin levels.

Itopride drug information | DrugsUpdate India

Itopride hydrochloride has been shown to accelerate gastric emptying in humans, dogs and rats. Higher acetylcholine increases GI peristalsis, increases the lower oesophageal sphincter pressure, stimulates gastric motility, accelerates gastric emptying, and improves gastro-duodenal coordination.

It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. There is evidence that itopride may have prokinetic effects throughout the gastrointestinal tract from the stomach to the invormation of prescrlbing colon.

Itopride Ganaton though is a safe drug but its response is not as per requirement. Lab interference Information Not Available. If you have the information you are welcome to respond, but please ensure that the information so provided is genuine and not misleading.

Reactions During Clinical Trials: The dose may be reduced according to the patient’s age and symptoms see Precautions.

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